SCHEMBL5426604

SCHEMBL5426604

C=CC=C=[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624152 0.68 APP (0.35) ALDH1A1TSHR
SCHEMBL5492830 0.66 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL5492834 0.66 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL439778 0.65 APP (0.41) ALDH1A1TSHRTGM2
SCHEMBL1663500 0.65 APP (0.41) ALDH1A1TSHRTGM2
SCHEMBL1477747 0.64 TSHR (0.41) ALDH1A1TSHRTGM2
SCHEMBL5881431 0.64 TSHR (0.41) ALDH1A1TSHRTGM2
Fluoride SCHEMBL27718732 0.62 TSHR (0.39) ALDH1A1TSHR
Styrene SCHEMBL3252714 0.60 ALDH1A1 (0.64) ALDH1A1TSHR
Styrene SCHEMBL5164856 0.60 ALDH1A1 (0.64) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297360-B2 Insulation film JSR CORPORATION (JP) 2007-11-20 US disclosed
US-20040110896-A1 Insulation film JSR CORPORATION (JP) 2004-06-10 US disclosed
EP-1427004-A2 Insulation film JSR Corporation (JP) 2004-06-09 EP disclosed