SCHEMBL5426992

SCHEMBL5426992

CN/C(=N\[N+](=O)[O-])N(Cc1cnc(Cl)s1)C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.41
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
BMP1 P13497 1/20 0.38
MAPT P10636 3/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 3/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5426996 1.00 RECQL (0.41) RECQLPOLBGAABMP1MAPT
SCHEMBL7840613 0.90 RECQL (0.37) RECQLPOLBGAABMP1MAPT
SCHEMBL7840615 0.90 RECQL (0.37) RECQLPOLBGAABMP1MAPT
SCHEMBL7838954 0.89 BMP1 (0.38) RECQLPOLBGAABMP1MAPT
SCHEMBL7838957 0.89 BMP1 (0.38) RECQLPOLBGAABMP1MAPT
SCHEMBL7837267 0.89 RECQL (0.39) RECQLPOLBGAABMP1MAPT
SCHEMBL7837268 0.89 RECQL (0.39) RECQLPOLBGAABMP1MAPT
SCHEMBL8196105 0.89 RECQL (0.38) RECQLPOLBGAABMP1MAPT
SCHEMBL8196106 0.89 RECQL (0.38) RECQLPOLBGAABMP1MAPT
SCHEMBL7829744 0.89 BMP1 (0.37) RECQLPOLBGAABMP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471372-B1 Novel substituted guanidine derivatives, their preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-11-21 EP claimed
EP-0471372-A1 Novel substituted guanidine derivatives, their preparation and use Takeda Chemical Industries, Ltd. (JP) 1992-02-19 EP claimed
EP-3392223-B1 GYPSUM BOARD YOSHINO GYPSUM CO (JP) 2021-09-08 EP disclosed
US-10968624-B2 Gypsum panel and method for producing gypsum panel YOSHINO GYPSUM CO., LTD. (JP) 2021-04-06 US disclosed
US-20180355605-A1 GYPSUM PANEL AND METHOD FOR PRODUCING GYPSUM PANEL YOSHINO GYPSUM CO., LTD. (JP) 2018-12-13 US disclosed
EP-3392223-A1 GYPSUM BOARD AND PROCESS FOR PRODUCING GYPSUM BOARD Yoshino Gypsum Co., Ltd. (JP) 2018-10-24 EP disclosed
US-20070039235-A1 Hardenable termite-controlling composition JAPAN ENVIROCHEMICALS, LTD. (JP) 2007-02-22 US disclosed
EP-0471372-B1 Novel substituted guanidine derivatives, their preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-11-21 EP disclosed
US-5256679-A Pesticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-26 US disclosed
EP-0471372-A1 Novel substituted guanidine derivatives, their preparation and use Takeda Chemical Industries, Ltd. (JP) 1992-02-19 EP disclosed