Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434984 | 0.92 | SIGMAR1 (0.39) | GAAHTR7HTR2AHTR1AHTR1D | |
| SCHEMBL5426449 | 0.91 | SIGMAR1 (0.44) | GAAHTR7HTR2AHTR1AHTR1D | |
| SCHEMBL5420044 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5425641 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5424611 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5417231 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5424707 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5428668 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5420038 | 0.90 | SIGMAR1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5437617 | 0.88 | GAA (0.36) | GAAHTR7HTR2AGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083965-B2 | Refrigerating machine oil | NIPPON OIL CORPORATION (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20070275865-A1 | Refrigerating Machine Oil | NIPPON OIL CORPORATION (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070257229-A1 | Refrigerating Machine Oil Composition | NIPPON OIL CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |