Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cryptolepine SCHEMBL5803104 | 0.98 | TERT (0.97) | TERTKMT2AMCL1KDM4EACHE | |
| Cryptolepine SCHEMBL8479701 | 0.98 | TERT (0.97) | TERTKMT2AMCL1KDM4EACHE | |
| Cryptolepine SCHEMBL8483526 | 0.98 | TERT (0.97) | TERTKMT2AMCL1KDM4EACHE | |
| SCHEMBL8484006 | 0.85 | TERT (0.73) | TERTKMT2AMCL1KDM4EACHE | |
| SCHEMBL29256991 | 0.85 | TERT (0.73) | TERTKMT2AMCL1RXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8482222 | 0.84 | TERT (0.71) | TERTKMT2AMCL1KDM4ESMN1; SMN2 | |
| SCHEMBL8478874 | 0.83 | TERT (0.70) | TERTKMT2AKDM4EACHEMAOA | |
| Hydrochloric Acid SCHEMBL8483810 | 0.82 | TERT (0.68) | TERTKMT2AKDM4EACHEMAOA | |
| Iodide SCHEMBL8855019 | 0.82 | TERT (0.68) | TERTKMT2AKDM4EACHEMAOA | |
| SCHEMBL9235969 | 0.80 | TERT (0.66) | TERTKMT2AKDM4EACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4578857-A1 | CRYPTOLEPINE SALT DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Nankai University (CN) | 2025-07-02 | — | — | EP | claimed |
| EP-4319788-A1 | REGULATION OF CELLS AND ORGANISMS | Tets, Victor (US) | 2024-02-14 | — | — | EP | claimed |
| CN-115385940-A | White leaf vine zinc (II) complex and application thereof | 玉林师范学院 | 2022-11-25 | — | — | CN | claimed |
| WO-2022214966-A1 | REGULATION OF CELLS AND ORGANISMS | TETS VICTOR (US) | 2022-10-13 | — | — | WO | claimed |
| CN-114762503-A | Application of ethanol extract of caulis et folium wilsonii and dictamnine in pesticide | 南开大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114736156-A | Preparation method and application of simplified derivatives of cryptolepine | 中捷四方生物科技股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114304169-A | Bactericidal composition containing cryptolepine analogue and small molecular phenolic compound and application of bactericidal composition in preventing and treating plant diseases | 兰州大学 | 2022-04-12 | — | — | CN | claimed |
| CN-114276346-A | Isochrysine analogue, preparation method and application of isochrysine analogue from fleroxacin | 河南大学 | 2022-04-05 | — | — | CN | claimed |
| CN-114276369-A | Isoleucinine analogs, preparation method and application of isoleucinine analogs from rufloxacin to isoleucinine analogs | 河南大学 | 2022-04-05 | — | — | CN | claimed |
| CN-113999250-A | Isoleucinine analogue prepared from ofloxacin as raw material, and preparation method and application thereof | 郑州工业应用技术学院 | 2022-02-01 | — | — | CN | claimed |
| CN-109090123-A | Application of the new cryptolepine derivative in prevention and treatment plant source germ | 兰州大学 | 2018-12-28 | — | — | CN | claimed |
| WO-2018035423-A1 | GENOME EDITING ENHANCERS | BLUEBIRD BIO, INC. (US) | 2018-02-22 | — | — | WO | claimed |
| US-20170071198-A1 | Process for the Production of Partially Polymerized Antimicrobial Silanol Quaternary Ammonium Compounds | NOVALENT, LTD. | 2017-03-16 | — | — | US | claimed |
| CN-104447772-A | Cryptolepine derivative, application of cryptolepine derivative as antibacterial agent as well as antibacterial drug prepared from cryptolepine derivative | FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIVERSITY | 2015-03-25 | — | — | CN | claimed |
| CN-103224500-A | Annular secondary amino substitution cryptolepine ramification and preparation method thereof and application of annular substitution cryptolepine ramification being used as anti-cancer drug | UNIV GUANGDONG TECHNOLOGY | 2013-07-31 | — | — | CN | claimed |
| US-5925647-A | TREATMENT OF INSULIN NON-INSULIN DEPENDENT DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | claimed |
| WO-1997036603-A1 | BIOCONTROL AGENTS FOR USE IN TREATMENT OF OPPORTUNISTIC INFECTIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-10-09 | — | — | WO | claimed |
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | claimed |
| US-5362726-A | Spiro-nonacyclic indoloquinoline alkaloid, cryptospirolepine | HEALTHSEARCH, INC. (US) | 1994-11-08 | — | — | US | claimed |
| WO-1994018203-A1 | ALKALOID COMPOUNDS EXTRACTED FROM CRYPTOLEPIS SANQUINOLENTA AND USES THEREOF | HEALTHSEARCH, INC. (US) | 1994-08-18 | — | — | WO | claimed |