SCHEMBL5428014

SCHEMBL5428014

COc1ccc(-c2ccc3ccccc3c2)c2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.60
ERN1 O75460 2/20 0.58
MAPT P10636 1/20 0.56
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
CYP2B6 P20813 1/20 0.51
CYP2C19 P33261 1/20 0.51
ALOX5 P09917 1/20 0.51
RAC1 P63000 2/20 0.50
CNR2 P34972 1/20 0.50
GSTP1 P09211 1/20 0.48
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1890125 0.93 NQO1 (0.56) NQO1ERN1MAPTESR1ESR2
SCHEMBL12031832 0.90 CYP11B2 (0.57) NQO1ERN1MAPTESR1ESR2
SCHEMBL12019776 0.90 CYP11B2 (0.57) NQO1ERN1MAPTESR1ESR2
SCHEMBL21132006 0.89 MAPT (0.50) NQO1ERN1MAPTESR1ESR2
SCHEMBL12019871 0.88 CYP11B2 (0.55) NQO1ERN1MAPTESR1ESR2
SCHEMBL12019938 0.88 CYP11B2 (0.55) NQO1ERN1MAPTESR1ESR2
SCHEMBL3193310 0.84 GSTP1 (0.64) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL3193631 0.82 GSTP1 (0.61) ESR1ESR2CYP1A2CYP3A4CYP2D6
SCHEMBL1892111 0.82 MAPT (0.52) NQO1MAPTCYP2C9CYP2C19IDO1
SCHEMBL3606605 0.81 PTPRC (0.57) NQO1ERN1MAPTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070212569-A1 ORGANOMETALLIC COMPLEX FOR ORGANIC LIGHT-EMITTING LAYER AND ORGANIC LIGHT-EMITTING DIODE USING THE SAME SFC CO., LTD. (KR) 2007-09-13 US disclosed