⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865632 | 0.79 | SLC22A6 (0.50) | — | |
| SCHEMBL7383379 | 0.79 | LMNA (0.39) | — | |
| SCHEMBL13208843 | 0.76 | — | — | |
| SCHEMBL636306 | 0.76 | — | — | |
| SCHEMBL12085019 | 0.74 | LMNA (0.41) | — | |
| SCHEMBL115227 | 0.73 | — | — | |
| SCHEMBL18902875 | 0.73 | — | — | |
| SCHEMBL158299 | 0.73 | — | — | |
| SCHEMBL28846261 | 0.73 | — | — | |
| SCHEMBL1980321 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-A | Aryl-linking compound as immunomodulator | 百时美施贵宝公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109504270-A | A kind of waterproof agent for building and preparation method thereof | 长沙小如信息科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-108290896-A | 2- phenyl -3,4- pyrrolin as phosphodiesterase inhibitors simultaneously [2,1-F] [1,2,4] triazone derivatives and application thereof | 托帕杜制药公司 | 2018-07-17 | — | — | CN | claimed |
| CN-1345308-A | Acetylenic alpha-amino acid based sulfonamide hydroxamic acid TACE inhibitors | AMERICAN CYANAMID CO (US) | 2002-04-17 | — | — | CN | claimed |
| CN-1078201-C | Prepn of contrast medium 'Dianhaichun' | JIANGSU PROV INST OF ATOMIC ME (CN) | 2002-01-23 | — | — | CN | claimed |
| EP-1144368-A2 | ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000044709-A2 | ACETYLENIC α-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | claimed |
| CN-1132743-A | Prepn of contrast medium 'Dianhaichun' | JIANGSU PROV INST OF ATOMIC ME (CN) | 1996-10-09 | — | — | CN | claimed |
| EP-0394311-A1 | RENIN INHIBITING PEPTIDES THAT CONTAIN AMINO AND HYDROXY DICARBOXYLIC ACIDS | THE UPJOHN COMPANY (US) | 1990-10-31 | — | — | EP | claimed |
| WO-1989004833-A1 | RENIN INHIBITING PEPTIDES THAT CONTAIN AMINO AND HYDROXY DICARBOXYLIC ACIDS | THE UPJOHN COMPANY (US) | 1989-06-01 | — | — | WO | claimed |
| CN-116354843-B | Method for synthesizing iopromide | 重庆圣华曦药业股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-116354843-A | Improved method for synthesizing iopromide and application of iopromide in injection | 重庆圣华曦药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-114671864-A | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-108290896-B | 2-phenyl-3, 4-dihydropyrrolo [2,1-F ] [1,2,4] triazinone derivatives and uses thereof | 托帕杜制药公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-109134289-B | Synthetic method and application of contrast agent intermediate | 成都西岭源药业有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |