SCHEMBL5429264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5429612	1.00	NPC1 (0.65)	NPC1RAB9AHPGDCYP1A2CYP2C19
	SCHEMBL5424850	0.98	NPC1 (0.62)	NPC1RAB9AHPGDCYP1A2CYP2C19
	SCHEMBL5428549	0.95	HDAC1 (0.58)	NPC1RAB9AHPGDCYP1A2CYP2C19
	SCHEMBL5427032	0.92	HDAC1 (0.62)	NPC1RAB9AHPGDCYP1A2CYP2C19
	SCHEMBL5422098	0.87	GRM5 (0.60)	NPC1RAB9AHPGDCYP1A2CYP2C19
	SCHEMBL21489956	0.85	SMYD3 (0.59)	HDAC1HDAC6
	SCHEMBL19701357	0.85	SMYD3 (0.59)	HDAC1HDAC6
	SCHEMBL26944377	0.84	HDAC6 (0.53)	HDAC1HDAC6KMT2A
	SCHEMBL7239293	0.83	GRM5 (0.59)	NPC1RAB9AHPGDCYP1A2CYP2C19
	SCHEMBL26804453	0.83	SMYD3 (0.63)	NPC1RAB9AHPGDCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.