Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.57 |
| ▸ | OXTR | P30559 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14500341 | 0.90 | AVPR2 (0.60) | AVPR2AVPR1AOXTR | |
| Hydrochloric Acid SCHEMBL5420707 | 0.89 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL14500331 | 0.79 | KDM4E (0.50) | AVPR2AVPR1AOXTRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5419258 | 0.78 | KDM4E (0.49) | AVPR2AVPR1AOXTRALDH1A1MAPT | |
| SCHEMBL5418938 | 0.77 | HDAC1 (0.54) | AVPR2AVPR1AOXTRALDH1A1NR3C1 | |
| SCHEMBL9389632 | 0.74 | AVPR2 (1.00) | AVPR2AVPR1AOXTRALDH1A1 | |
| SCHEMBL5639987 | 0.73 | TP53 (0.51) | MAPTTHRBTP53LMNA | |
| SCHEMBL5420247 | 0.72 | HDAC1 (0.50) | AVPR2AVPR1AOXTRALDH1A1NR3C1 | |
| SCHEMBL5426483 | 0.72 | IDO1 (0.51) | AVPR2AVPR1AOXTRALDH1A1THRB | |
| SCHEMBL5420242 | 0.72 | HDAC1 (0.50) | AVPR2AVPR1AOXTRALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-20030158177-A1 | Treating or preventing obesity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1283199-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158177-A1 | Treating or preventing obesity | MCHR1, MC1R, NPY1R | AVPR2 133/4885AVPR1A 136/4885OXTR 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.