Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5419258 | 0.99 | KDM4E (0.49) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL5423637 | 0.81 | PDK1 (0.49) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL7830813 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL5429447 | 0.79 | AVPR2 (0.57) | ALDH1A1HTTSMN1; SMN2MAPTTSHR | |
| SCHEMBL8809305 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL16595915 | 0.76 | NPC1 (0.57) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL16595916 | 0.75 | L3MBTL1 (0.51) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL16595911 | 0.74 | NPC1 (0.50) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL5696394 | 0.74 | NOTUM (0.59) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL30767099 | 0.74 | NOTUM (0.59) | KDM4EALDH1A1HTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |