Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482454 | 0.90 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28274622 | 0.89 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| Propene SCHEMBL28052131 | 0.89 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15276 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5446210 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL20567404 | 0.88 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2417551 | 0.88 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29961454 | 0.88 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29962797 | 0.88 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23437 | 0.88 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367096-B2 | Polymers having covalently bound therapeutic agents | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20070020308-A1 | Polymers having covalently bound therapeutic agents | BOSTON SCIENTIFIC SCIMED, INC. | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020308-A1 | Polymers having covalently bound therapeutic agents | CD44, CD47, PAICS | TSHR 4104/4885THRB 4616/4885POLB 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.