Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434363 | 0.81 | MEN1 (0.68) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL28987049 | 0.78 | MEN1 (0.63) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL12531030 | 0.77 | HSD17B10 (0.68) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL3817884 | 0.76 | CA2 (0.70) | KMT2AMEN1ALDH1A1HPGDCYP1A2 | |
| Benzoic Acid SCHEMBL5079271 | 0.76 | HSD17B10 (0.73) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL7538616 | 0.75 | KMT2A (0.60) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL4920225 | 0.75 | HDAC6 (0.61) | KMT2AMEN1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL13219070 | 0.74 | HSD17B10 (0.63) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL4889683 | 0.74 | KDM4E (1.00) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL12305654 | 0.74 | HSD17B10 (0.69) | KMT2AMEN1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007530524-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1730103-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | Pfizer Limited (GB) | 2006-12-13 | — | — | EP | claimed |
| WO-2005092840-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | claimed |