SCHEMBL5433249

SCHEMBL5433249

O=C(CCNC(=O)c1ccc(-n2ccncc2=O)cc1)NS(=O)(=O)c1cc2ccc(Cl)cc2[nH]1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 7/20 0.41
F9 P00740 1/20 0.39
ALOX15 P16050 3/20 0.37
CNR1 P21554 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5442104 0.87 F10 (0.53) F10CNR1
SCHEMBL5427726 0.86 F10 (0.38) F10F9ALOX15CNR1
SCHEMBL5432956 0.86 F10 (0.38) F10F9ALOX15CNR1
SCHEMBL5440830 0.83 F10 (0.39) F10F9CNR1
SCHEMBL5439007 0.79 MAPT (0.50) F10
SCHEMBL5434183 0.78 F10 (0.44) F10
SCHEMBL5436857 0.78 F10 (0.44) F10
SCHEMBL5436888 0.77 F10 (0.40) F10
SCHEMBL5437504 0.76 RHOC (0.52) F10
SCHEMBL5445270 0.73 F10 (0.50) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070129361-A1 LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS QIAO JENNIFER X 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129361-A1 LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS PEPD, XPNPEP1, METAP1 F10 46/4885F9 59/4885ALOX15 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.