Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12522773 | 1.00 | MGAM (0.41) | MGAMGAASIMGAM2TET2 | |
| SCHEMBL5433710 | 1.00 | MGAM (0.41) | MGAMGAASIMGAM2TET2 | |
| SCHEMBL12451755 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2TET2 | |
| SCHEMBL31484781 | 0.81 | GAA (0.39) | MGAMGAASIMGAM2TET2 | |
| SCHEMBL18891139 | 0.80 | ALDH1A1 (0.32) | TET2ALDH1A1KDM4ETDP1EGLN1 | |
| SCHEMBL22213919 | 0.80 | ALDH1A1 (0.32) | TET2ALDH1A1KDM4ETDP1EGLN1 | |
| SCHEMBL22774906 | 0.80 | ALDH1A1 (0.32) | TET2ALDH1A1KDM4ETDP1EGLN1 | |
| SCHEMBL13578878 | 0.79 | GAA (0.38) | MGAMGAASIMGAM2TET2 | |
| SCHEMBL7789785 | 0.79 | GAA (0.38) | MGAMGAASIMGAM2TET2 | |
| SCHEMBL10749678 | 0.78 | ALDH1A1 (0.31) | TET2ALDH1A1KDM4ETDP1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238599-A1 | HETEROCYCLIC COMPOUNDS AS MEK INHIBITORS | CHEMIZON, A DIVISION OF OPTOMAGIC CO., LTD. (KR) | 2012-09-20 | — | — | US | disclosed |
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1659123-A1 | BICYCLIC PYRAZOLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082908-A1 | Bicycle pyrazole derivative | DPP4, DPP7, DPP3 | MGAM 1650/4885GAA 3757/4885SI 860/4885 |
| US-20120238599-A1 | HETEROCYCLIC COMPOUNDS AS MEK INHIBITORS | BRAF, MAP3K1, MAP3K11 | MGAM 3654/4885GAA 3365/4885SI 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.