Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CD38 | P28907 | 10/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177212 | 0.91 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5177336 | 0.85 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5178046 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4911084 | 0.81 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5175509 | 0.75 | KAT2B (0.37) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5177384 | 0.74 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4909027 | 0.72 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4912478 | 0.71 | CYP3A4 (0.53) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4911581 | 0.69 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4912610 | 0.69 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287726-A1 | 5-Substituted 1H-Pyrrolo [3,2-B] Pyridines | ALTANA PHARMA AG (DE) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287726-A1 | 5-Substituted 1H-Pyrrolo [3,2-B] Pyridines | GIPR, VIP, PGC | CYP3A4 367/4885CYP2C9 552/4885CYP1A2 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.