SCHEMBL5434744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14388634	0.90	TRPV4 (0.59)	TRPV4NPC1POLBRAB9ASMN1; SMN2
	SCHEMBL5434750	0.82	NPC1 (0.40)	TRPV4NPC1POLBRAB9ASMN1; SMN2
	SCHEMBL5431334	0.81	TRPV4 (0.73)	TRPV4RAB9ACTSBCTSSCTSK
	SCHEMBL5449491	0.80	TRPV4 (0.54)	TRPV4SMN1; SMN2ALDH1A1CTSLCTSB
	SCHEMBL4136396	0.80	TRPV4 (0.70)	TRPV4RAB9ACTSLCTSBCTSS
	SCHEMBL5444152	0.80	TRPV4 (0.59)	TRPV4ALDH1A1CTSLCTSBCTSS
	SCHEMBL5441701	0.80	TRPV4 (0.57)	TRPV4CTSLCTSBCTSSCTSK
	SCHEMBL5429305	0.78	TRPV4 (0.63)	TRPV4MAPTCTSLCTSBCTSS
	SCHEMBL5434009	0.76	TRPV4 (0.53)	TRPV4CTSLCTSBCTSSCTSK
	SCHEMBL5435992	0.76	TRPV4 (0.52)	TRPV4SMN1; SMN2ALDH1A1CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.