Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 6/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.37 |
| ▸ | PDE6D | O43924 | 2/20 | 0.37 |
| ▸ | PDE6A | P16499 | 2/20 | 0.37 |
| ▸ | PDE6G | P18545 | 2/20 | 0.37 |
| ▸ | PDE6B | P35913 | 2/20 | 0.37 |
| ▸ | PDE6C | P51160 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867703 | 0.83 | PTPN11 (0.38) | MAP4K4PDE2APDE10APDE6DPDE6A | |
| SCHEMBL14358116 | 0.82 | PDE10A (0.39) | MAP4K4PDE2APDE10APDE6DPDE6A | |
| SCHEMBL29692882 | 0.81 | EGFR (0.41) | MAP4K4PDE2APDE10APDE6DPDE6A | |
| SCHEMBL2770307 | 0.81 | KCNH2 (0.36) | MAP4K4PDE2APDE10APDE6DPDE6A | |
| SCHEMBL30775555 | 0.81 | MAP4K4 (0.41) | MAP4K4KDM4ENPC1GAAMAPT | |
| SCHEMBL3379185 | 0.81 | MAP4K4 (0.41) | MAP4K4KDM4ENPC1GAAMAPT | |
| SCHEMBL1075499 | 0.81 | EGFR (0.41) | MAP4K4PDE2APDE10APDE6DPDE6A | |
| SCHEMBL4507986 | 0.81 | MAP4K4 (0.41) | MAP4K4PDE10APIK3CDPIP5K1CPIK3CA | |
| SCHEMBL2038287 | 0.81 | MAP4K4 (0.41) | MAP4K4KDM4ENPC1GAAMAPT | |
| SCHEMBL29692824 | 0.81 | KCNH2 (0.36) | MAP4K4PDE2APDE10APDE6DPDE6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | TOP1, TOP2A, TOP2B | MAP4K4 2777/4885KDM4E 2755/4885NPC1 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.