Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.64 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845529 | 0.83 | PARP1 (0.50) | MTNR1APARP1L3MBTL1CYP2C19CDC7 | |
| SCHEMBL256379 | 0.83 | PARP1 (0.50) | MTNR1APARP1L3MBTL1CYP2C19CDC7 | |
| Bromide SCHEMBL28427695 | 0.82 | PARP1 (0.49) | MTNR1APARP1L3MBTL1CYP2C19CDC7 | |
| SCHEMBL29523425 | 0.80 | — | — | |
| SCHEMBL709685 | 0.80 | AXL (1.00) | AXLNUDT1DAODYRK1ACDK8 | |
| SCHEMBL17837 | 0.80 | — | — | |
| Methane SCHEMBL14738986 | 0.78 | AXL (0.95) | AXLNUDT1DAODYRK1ACDK8 | |
| Potassium SCHEMBL30760557 | 0.78 | AXL (0.95) | AXLNUDT1DAODYRK1ACDK8 | |
| Ammonia Solution, Strong SCHEMBL27486357 | 0.78 | AXL (0.95) | AXLNUDT1DAODYRK1ACDK8 | |
| SCHEMBL27753650 | 0.78 | AXL (0.95) | AXLNUDT1DAODYRK1ACDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185079-A1 | Therapeutic agents I | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185079-A1 | Therapeutic agents I | HTT, GRIN2A, GRIN1 | AXL 4877/4885NUDT1 3053/4885MTNR1A 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.