Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214818 | 0.83 | CYP1A2 (0.53) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5437481 | 0.82 | CYP1A2 (0.56) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL3214847 | 0.81 | CYP1A2 (0.54) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5432959 | 0.80 | CYP1A2 (0.53) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL38656054 | 0.80 | CYP1A2 (0.56) | CYP1A2KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL2415294 | 0.79 | CYP1A2 (0.51) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5437280 | 0.78 | CYP1A2 (0.50) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5471814 | 0.77 | ALDH1A1 (0.50) | CYP1A2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL5435177 | 0.77 | CYP1A2 (0.49) | CYP1A2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5440792 | 0.75 | CYP1A2 (0.47) | CYP1A2HDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167631-A1 | Novel herbicides | Luthy, Christoph (CH) | 2007-07-19 | — | — | US | disclosed |
| EP-1692108-A1 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058830-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058831-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058037-A1 | PICOLINYLPYRAZOLES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167631-A1 | Novel herbicides | DDT, CYP1A1, CYP1B1 | CYP1A2 16/4885HDAC3 787/4885HDAC4 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.