Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.40 |
| ▸ | THRA | P10827 | 5/20 | 0.40 |
| ▸ | FADS1 | O60427 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398710 | 0.90 | THRB (0.42) | THRBTHRAMEN1KMT2A | |
| SCHEMBL5415373 | 0.87 | THRB (0.43) | THRBTHRAMEN1KMT2A | |
| SCHEMBL5327191 | 0.84 | THRB (0.40) | THRBTHRA | |
| SCHEMBL5322901 | 0.81 | THRB (0.40) | THRBTHRA | |
| SCHEMBL5437353 | 0.81 | THRB (0.40) | THRBTHRAMEN1KMT2A | |
| SCHEMBL5325041 | 0.79 | THRB (0.39) | THRBTHRA | |
| SCHEMBL5324548 | 0.78 | POLB (0.56) | MEN1KMT2A | |
| SCHEMBL5327221 | 0.77 | THRB (0.39) | THRBTHRAFADS1 | |
| SCHEMBL5326327 | 0.76 | THRB (0.55) | THRBTHRA | |
| SCHEMBL5329537 | 0.76 | THRB (0.43) | THRBTHRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |