SCHEMBL54380

SCHEMBL54380

Oc1c(Cl)cc(Cl)c(Cl)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 10/20 1.00
HPGD P15428 8/20 1.00
TSHR P16473 8/20 1.00
MAPK1 P28482 3/20 1.00
CASP1 P29466 1/20 0.67
CYP3A4 P08684 7/20 0.59
HSP90AA1 P07900 3/20 0.56
MEN1 O00255 3/20 0.56
LMNA P02545 3/20 0.56
MAPT P10636 3/20 0.56
KMT2A Q03164 3/20 0.56
ALOX15 P16050 3/20 0.56
ALOX12 P18054 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
RECQL P46063 2/20 0.56
THRB P10828 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
HIF1A Q16665 2/20 0.56
HTR1A P08908 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364629 1.00 HSD17B10 (1.00) HSD17B10HPGDTSHRMAPK1CASP1
Pentachlorophenol SCHEMBL10548213 0.88 HSD17B10 (0.78) HSD17B10HPGDTSHRMAPK1CASP1
SCHEMBL68191 0.87 HSD17B10 (0.77) HSD17B10HPGDTSHRMAPK1CASP1
Acetic Acid SCHEMBL28404451 0.85 HSD17B10 (0.73) HSD17B10HPGDTSHRMAPK1CASP1
SCHEMBL15478243 0.84 HSD17B10 (0.71) HSD17B10HPGDTSHRMAPK1CASP1
SCHEMBL1259609 0.83 HSD17B10 (0.70) HSD17B10HPGDTSHRMAPK1CASP1
SCHEMBL5487549 0.82 HSD17B10 (0.67) HSD17B10HPGDTSHRMAPK1CASP1
SCHEMBL30631745 0.81 HSD17B10 (0.77) HSD17B10HPGDTSHRMAPK1CASP1
SCHEMBL11832897 0.81 HSD17B10 (0.77) HSD17B10HPGDTSHRMAPK1CASP1
Pentachlorophenol SCHEMBL29158480 0.81 HSD17B10 (0.88) HSD17B10HPGDTSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5370 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118162109-A G-C of organic functional group COFs/nitrogen vacancy3N4Material, preparation method and application thereof 哈尔滨工业大学 2024-06-11 CN claimed
CN-118150714-A Method for detecting aromatic substances in atmospheric particulates 中国科学院大连化学物理研究所 2024-06-07 CN claimed
CN-118126831-A Euglena extracellular metabolite and application thereof in environmental treatment 深圳元育生物科技有限公司 2024-06-04 CN claimed
WO-2024108437-A1 METHOD FOR PREPARING PD/NI3S2/NF NANOSHEET ARRAY ELECTRODE BY MEANS OF IN-SITU VULCANIZATION ELECTRODEPOSITION, AND EHDC METHOD 苏州大学 2024-05-30 WO claimed
CN-118079911-A Preparation method and application of cuprous oxide/titanium dioxide photocatalyst 中国石油大学(华东) 2024-05-28 CN claimed
CN-117925094-A Functional finishing paint for maintaining pneumatic appearance of ceramic heat-resistant coating and preparation method thereof 湖北航聚科技股份有限公司 2024-04-26 CN claimed
EP-4356737-A2 BIOCIDE Purgos ApS (DK) 2024-04-24 EP claimed
CN-113893855-B Resin fibrous mesoporous SiO 2 Loaded with Fe 2 O 3 Catalyst, preparation method and application thereof 苏州大学 2024-03-26 CN claimed
CN-117682598-A Harmless treatment device and control method for chlorophenols compounds in wastewater 航天国华生态环境有限公司 2024-03-12 CN claimed
CN-116966472-B Efficient fly ash detoxification method based on finite field Fenton-like 南京大学 2024-03-08 CN claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed
US-4182860-A FREE-FLOWING, PURIFICATION, ENHANCED OIL RECOVERY LASKIN ALLEN I (US) 1980-01-08 US claimed
US-4160114-A ACID CATALYST WITH SULFUR CONTAINING CO-CATALYST REICHHOLD CHEMICALS, INC. (US) 1979-07-03 US claimed
US-4154964-A BY TREATMENT WITH COUNTERCURRENT FLOW OF PHOSPHORIC ACID UNDER A TEMPERATURE GRADIENT STAMICARBON, B.V. (NL) 1979-05-15 US claimed
US-4116879-A Quaternary hydroxyalkyl tertiary amine bases as polyurethane catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 1978-09-26 US claimed
US-4060468-A TUNGSTEN CONTAINING THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-11-29 US claimed
US-4039587-A Method of preparing polynuclear, halogenated, aromatic benzyl ethers DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-08-02 US claimed
US-3988267-A Quaternary hydroxyalkyl tertiary amine bases as polyurethane catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 1976-10-26 US claimed
US-3953530-A Process for making o- and p-chlorophenols S. A. TEXACO BELGIUM N.V. (BE) 1976-04-27 US claimed
US-3931000-A COALESCING DIALYSIS THE DOW CHEMICAL COMPANY (US) 1976-01-06 US claimed