Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | AHR | P35869 | 8/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773713 | 0.82 | AHR (0.70) | HSD17B10TSHRAHRCYP1B1TTR | |
| SCHEMBL29364629 | 0.82 | HSD17B10 (1.00) | HSD17B10HPGDTSHRMAPK1TTR | |
| SCHEMBL54380 | 0.82 | HSD17B10 (1.00) | HSD17B10HPGDTSHRMAPK1TTR | |
| SCHEMBL29497479 | 0.82 | AHR (0.68) | HSD17B10HPGDTSHRMAPK1AHR | |
| SCHEMBL10084006 | 0.82 | AHR (0.68) | HSD17B10HPGDTSHRMAPK1AHR | |
| Polychlorinated Biphenyl 126 SCHEMBL6535350 | 0.77 | AHR (1.00) | HSD17B10TSHRMAPK1AHRCYP1B1 | |
| Polychlorinated Biphenyl 126 SCHEMBL308662 | 0.77 | AHR (1.00) | HSD17B10TSHRMAPK1AHRCYP1B1 | |
| Polychlorinated Biphenyl 126 SCHEMBL6942325 | 0.77 | AHR (1.00) | HSD17B10TSHRMAPK1AHRCYP1B1 | |
| SCHEMBL8773697 | 0.77 | AHR (0.71) | HSD17B10HPGDTSHRAHRCYP1B1 | |
| SCHEMBL29769221 | 0.76 | AHR (1.00) | HSD17B10TSHRMAPK1AHRCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |