Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 5/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434826 | 1.00 | CCR1 (0.37) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL5434779 | 0.98 | CCR1 (0.38) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL4140995 | 0.93 | CCR1 (0.38) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL4130817 | 0.92 | CCR1 (0.38) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL5439621 | 0.92 | CCR1 (0.38) | CCR1ADAM17TLR4BMP1OPRL1 | |
| SCHEMBL5429196 | 0.90 | CCR1 (0.40) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL4142970 | 0.89 | CCR1 (0.39) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL4141707 | 0.88 | CCR1 (0.39) | CCR1ADAM17TLR4EPHX2NPC1 | |
| SCHEMBL5434632 | 0.85 | CCR1 (0.39) | CCR1ADAM17TLR4EPHX2BMP1 | |
| SCHEMBL4128183 | 0.85 | CCR1 (0.37) | CCR1ADAM17TLR4EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259965-A1 | Acyclic 1,3-Diamine And Uses Therefor | SMITHKLINE BEECHAM CORPORATION | 2007-11-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259965-A1 | Acyclic 1,3-Diamine And Uses Therefor | TRPV4, TRPC4, TRPV1 | CCR1 511/4885ADAM17 3043/4885TLR4 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.