Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445591 | 0.92 | ALDH1A1 (0.51) | ALDH1A1MAPTRECQLF10F2 | |
| SCHEMBL5440482 | 0.90 | EPHX2 (0.53) | ALDH1A1MAPTRECQLF10F2 | |
| SCHEMBL5433922 | 0.89 | F10 (0.51) | ALDH1A1MAPTRECQLF10USP2 | |
| SCHEMBL5439338 | 0.86 | MAPT (0.49) | MAPTF10F2RAB9ANAMPT | |
| SCHEMBL5440538 | 0.84 | MAPT (0.49) | ALDH1A1MAPTF10F2ATM | |
| SCHEMBL5433458 | 0.84 | F10 (0.45) | ALDH1A1F10CNR1EPHX2 | |
| SCHEMBL5438150 | 0.83 | F10 (0.45) | ALDH1A1MAPTRECQLF10F2 | |
| SCHEMBL5433090 | 0.81 | F10 (0.52) | ALDH1A1MAPTRECQLF10USP2 | |
| SCHEMBL5428307 | 0.81 | F10 (0.44) | ALDH1A1MAPTRECQLF10F2 | |
| SCHEMBL5433247 | 0.81 | MAPT (0.54) | ALDH1A1MAPTF10F2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | QIAO JENNIFER X | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | PEPD, XPNPEP1, METAP1 | ALDH1A1 1204/4885MAPT 4212/4885RECQL 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.