SCHEMBL5438604

SCHEMBL5438604

CNCC(N)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24046072 1.00
SCHEMBL5019147 0.83
SCHEMBL9195134 0.77
SCHEMBL44252 0.75
SCHEMBL12583467 0.75
SCHEMBL12583400 0.75
SCHEMBL28288573 0.73 ALDH1A1 (0.33)
SCHEMBL8226404 0.73
SCHEMBL22164756 0.73
SCHEMBL14067609 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024148272-A1 AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2024-07-11 WO disclosed
US-20220056052-A1 QUINAZOLINE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC 2022-02-24 US disclosed
EP-3902787-A1 QUINAZOLINE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS Riboscience LLC (US) 2021-11-03 EP disclosed
WO-2020140001-A1 QUINAZOLINE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2020-07-02 WO disclosed
CN-110461926-A Organic polymeric aerogels comprising microstructures BLUESHIFT INTERNATIONAL MAT INC 2019-11-15 CN disclosed
CN-110114390-A Fiber reinforcement organic polymer aeroge 蓝移材料有限公司 2019-08-09 CN disclosed
CN-108699277-A Polymeric aerogels with improved mechanical and thermal properties 蓝移材料有限公司 2018-10-23 CN disclosed
CN-108348871-A Highly branched, non-crosslinked aerogels, method for the production thereof and use thereof 蓝移材料有限公司 2018-07-31 CN disclosed
US-20180085466-A1 OPTICAL PROBES FOR MATRIX METALLOPROTEINASES THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2018-03-29 US disclosed
WO-2017044434-A1 SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-03-16 WO disclosed
US-4617138-A DISPERSANTS CHEVRON RESEARCH COMPANY (US) 1986-10-14 US disclosed
US-4614603-A Modified succinimides (III) CHEVRON RESEARCH COMPANY (US) 1986-09-30 US disclosed
US-4614522-A Fuel compositions containing modified succinimides (VI) CHEVRON RESEARCH COMPANY (US) 1986-09-30 US disclosed
US-4612132-A OIL AND FUEL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1986-09-16 US disclosed
US-4609378-A Modified succinimides (VIII) CHEVRON RESEARCH COMPANY (US) 1986-09-02 US disclosed
US-4608185-A Modified succinimides (VI) CHEVRON RESEARCH COMPANY (US) 1986-08-26 US disclosed
EP-0183478-A2 Glycidol modified succinimides CHEVRON RESEARCH COMPANY (US) 1986-06-04 EP disclosed
US-4584117-A Dispersant additives for lubricating oils and fuels CHEVRON RESEARCH COMPANY (US) 1986-04-22 US disclosed
EP-0172733-A2 Additive for lubricating oils and hydrocarbon fuels CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1986-02-26 EP disclosed
EP-0169715-A2 Modified succinimides for use in lubricating oils and hydrocarbon fuels CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1986-01-29 EP disclosed