Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623732 | 0.88 | TP53 (0.43) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL28570773 | 0.87 | RECQL (0.42) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL938334 | 0.86 | RECQL (0.37) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL28952158 | 0.86 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11123412 | 0.84 | RECQL (0.38) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL238534 | 0.82 | SPHK1 (0.45) | TP53CA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL1838532 | 0.82 | SPHK1 (0.45) | TP53CA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL239716 | 0.82 | SPHK1 (0.45) | TP53CA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL239692 | 0.82 | SPHK1 (0.45) | TP53CA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL15646327 | 0.82 | SPHK1 (0.45) | TP53CA1PSMD14PLA2G1BMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267077-A | CATIONIC SURFACTANT, ANIONIC SURFACTANT AND A SOLVENT; SOFTENING AND ANTISTATIC | KAO SOAP CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-20070118998-A1 | Methods for laundering delicate garments in a washing machine | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-31 | — | — | US | disclosed |
| US-7185380-B2 | Methods for laundering delicate garments in a washing machine comprising a woven acrylic coated polyester garment container | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-06 | — | — | US | disclosed |
| EP-1422334-A2 | Methods for laundering delicate garments in a washing machine | The Procter & Gamble Company (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20030008799-A1 | Methods for laundering delicate garments in a washing machine | THE PROCTER & GAMBLE COMPANY (US) | 2003-01-09 | — | — | US | disclosed |
| EP-1222331-A2 | METHODS FOR LAUNDERING DELICATE GARMENTS IN A WASHING MACHINE | The Procter & Gamble Company (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001025525-A2 | METHODS FOR LAUNDERING DELICATE GARMENTS IN A WASHING MACHINE | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-12 | — | — | WO | disclosed |
| US-4267077-A | CATIONIC SURFACTANT, ANIONIC SURFACTANT AND A SOLVENT; SOFTENING AND ANTISTATIC | KAO SOAP CO., LTD. (JP) | 1981-05-12 | — | — | US | disclosed |