Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439561 | 0.86 | RECQL (0.40) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL28570773 | 0.85 | RECQL (0.42) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL938334 | 0.85 | RECQL (0.37) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL29165752 | 0.84 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL7184129 | 0.84 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL10361507 | 0.83 | DNM1 (0.48) | LSSDNM1HTTHSP90AA1RAD52 | |
| SCHEMBL28190830 | 0.83 | DNM1 (0.48) | LSSDNM1HTTHSP90AA1RAD52 | |
| SCHEMBL924083 | 0.83 | DNM1 (0.48) | LSSDNM1HTTHSP90AA1RAD52 | |
| SCHEMBL1063760 | 0.83 | DNM1 (0.48) | LSSDNM1HTTHSP90AA1RAD52 | |
| SCHEMBL9635335 | 0.83 | DNM1 (0.48) | LSSDNM1HTTHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703926-A | Flame-retardant aromatic polycarbonate resin composition and molded product thereof | 帝人株式会社 | 2023-02-17 | — | — | CN | disclosed |