Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330333 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL30499789 | 0.85 | — | — | |
| SCHEMBL905930 | 0.85 | TSHR (0.57) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL2137245 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL23748798 | 0.83 | — | — | |
| SCHEMBL356135 | 0.83 | — | — | |
| SCHEMBL1075549 | 0.81 | TSHR (0.50) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL5446780 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LMNATSHRMAPTABCC4 | |
| Hydrochloric Acid SCHEMBL30480704 | 0.81 | CYP1A2 (0.47) | ALDH1A1LMNATSHRCYP3A4GAA | |
| SCHEMBL11357979 | 0.81 | CYP1A2 (0.47) | ALDH1A1LMNATSHRCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003485-A1 | Contrast agents | KLAVENESS JO | 2007-01-04 | — | — | US | disclosed |
| US-20050232865-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-10-20 | — | — | US | disclosed |
| US-20040131549-A1 | Ultrasonic diagnosis; crosslinked protein forming gas containing vesicles; stability; high speed elimination | NYCOMED IMAGING AS. | 2004-07-08 | — | — | US | disclosed |
| EP-0576521-B2 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2004-02-04 | — | — | EP | disclosed |
| US-20030031629-A1 | Contrast agents | NYCOMED IMAGING AS | 2003-02-13 | — | — | US | disclosed |
| US-6107422-A | HAVING NOVEL MICROSTRUCTURE; ELASTOMERS, MOLDING MATERIALS, ADHESIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| US-5919753-A | Cross-linking agent | NYCOMED IMAGING AS (NO) | 1999-07-06 | — | — | US | disclosed |
| EP-0807441-A2 | Improvements in or relating to contrast agents | NYCOMED IMAGING AS (NO) | 1997-11-19 | — | — | EP | disclosed |
| EP-0576521-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1997-09-03 | — | — | EP | disclosed |
| US-5529766-A | Contrast agents | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |
| EP-0577659-B1 | CROSS-LINKING AGENT | NYCOMED IMAGING AS (NO) | 1996-01-17 | — | — | EP | disclosed |
| EP-0577659-A1 | CROSS-LINKING AGENT. | HOLMES MICHAEL JOHN (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0576521-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS. | NYCOMED IMAGING AS (NO) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992017436-A1 | CROSS-LINKING AGENT | HOLMES, MICHAEL, JOHN (GB) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992017213-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1992-10-15 | — | — | WO | disclosed |