Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 5/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.43 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438615 | 0.85 | F10 (0.59) | F10 | |
| SCHEMBL5437504 | 0.81 | RHOC (0.52) | F10HTT | |
| SCHEMBL5437953 | 0.80 | F10 (0.51) | F10LMNANAMPT | |
| SCHEMBL5432956 | 0.76 | F10 (0.38) | F10 | |
| SCHEMBL5433754 | 0.76 | F10 (0.39) | F10 | |
| SCHEMBL5438595 | 0.75 | F10 (0.38) | F10NPSR1 | |
| SCHEMBL5443232 | 0.74 | MAPT (0.61) | F10LMNANAMPT | |
| SCHEMBL5433503 | 0.73 | CYP1A2 (0.49) | F10 | |
| SCHEMBL1405889 | 0.72 | F10 (0.52) | F10HTT | |
| SCHEMBL5433368 | 0.71 | F10 (0.40) | F10LMNAHTTNAMPTCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | QIAO JENNIFER X | 2007-06-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129361-A1 | LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | PEPD, XPNPEP1, METAP1 | F10 46/4885LMNA 1088/4885HTT 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.