SCHEMBL5440385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5450462	0.93	PKM (0.45)	PKMHDAC1HDAC2HDAC3HDAC4
	SCHEMBL5638767	0.80	PKM (0.53)	PKMNPC1MAPTRAB9A
	SCHEMBL5640214	0.78	PKM (0.51)	PKMNPC1MAPTRAB9A
	SCHEMBL5449011	0.78	PKM (0.43)	PKMHDAC1HDAC3HDAC6MAOB
	SCHEMBL5640663	0.74	PKM (0.46)	PKMDRD2DRD3NPC1MAPT
	SCHEMBL5637576	0.74	PKM (0.50)	PKMNPC1RAB9A
	SCHEMBL5639671	0.74	PKM (0.47)	PKMHDAC1HDAC2HDAC3HDAC4
	SCHEMBL5638598	0.74	HDAC1 (0.46)	PKMHDAC1HDAC2DRD2DRD3
	SCHEMBL5438532	0.72	HDAC6 (0.42)	PKMHDAC1HDAC2HDAC3HDAC4
	SCHEMBL5640786	0.71	MAPT (0.52)	PKMNPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.