Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360087 | 0.90 | HTR6 (0.78) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5374506 | 0.90 | HTR6 (0.78) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5448011 | 0.89 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5372081 | 0.88 | HTR6 (0.80) | HTR6KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL5379591 | 0.88 | HTR6 (0.80) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5475378 | 0.81 | HTR6 (0.68) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5361658 | 0.79 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5363505 | 0.79 | HTR6 (0.83) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5375838 | 0.78 | HTR6 (0.78) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5443199 | 0.78 | HTR6 (0.85) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138611-A1 | 3-(HETEROCYCLYL)-N-(ARYLSULFONYL)INDOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-12-06 | — | — | WO | disclosed |