Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 5/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440749 | 1.00 | EPHX2 (0.47) | EPHX2IKBKBMAPK8KCNH2NOS2 | |
| SCHEMBL5434480 | 0.80 | EPHX2 (0.46) | EPHX2NOS2NOS1NOS3ALDH1A1 | |
| SCHEMBL5434476 | 0.80 | EPHX2 (0.46) | EPHX2NOS2NOS1NOS3ALDH1A1 | |
| SCHEMBL4885177 | 0.78 | NOS3 (0.45) | NOS2NOS1NOS3ALDH1A1MAPT | |
| SCHEMBL14066257 | 0.78 | NOS3 (0.45) | NOS2NOS1NOS3ALDH1A1MAPT | |
| SCHEMBL4885189 | 0.78 | NOS3 (0.45) | NOS2NOS1NOS3ALDH1A1MAPT | |
| SCHEMBL5427966 | 0.77 | EPHX2 (0.45) | EPHX2KCNH2 | |
| SCHEMBL5427969 | 0.77 | EPHX2 (0.45) | EPHX2KCNH2 | |
| SCHEMBL5424945 | 0.76 | JAK2 (0.38) | KCNH2NOS2NOS1NOS3ALDH1A1 | |
| SCHEMBL5424947 | 0.76 | JAK2 (0.38) | KCNH2NOS2NOS1NOS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225333-A1 | 3-Heterocyclyl-4-Phenyl-Triazole Derivatives as Inhibitors of the Vasopressin Via Receptor | BRYANS JUSTIN S | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225333-A1 | 3-Heterocyclyl-4-Phenyl-Triazole Derivatives as Inhibitors of the Vasopressin Via Receptor | AVPR2, RXFP3, AVPR1A | EPHX2 1357/4885IKBKB 2026/4885MAPK8 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.