Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 5/20 | 0.49 |
| ▸ | GABRD | O14764 | 5/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664542 | 1.00 | POLB (0.57) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL15119910 | 0.86 | GABRA1 (0.49) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL472553 | 0.82 | KMT2A (0.62) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL30397090 | 0.82 | KMT2A (0.62) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL16635110 | 0.81 | KDM4E (0.58) | POLBKMT2AGAAMAPTKDM4E | |
| Ammonia Solution, Strong SCHEMBL28197882 | 0.81 | KMT2A (0.60) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL2140228 | 0.81 | NPC1 (0.50) | KMT2AMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13969985 | 0.80 | GABRA1 (0.44) | POLBGAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL30450401 | 0.79 | POLB (0.50) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL22413472 | 0.79 | POLB (0.50) | POLBKMT2AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167631-A1 | Novel herbicides | Luthy, Christoph (CH) | 2007-07-19 | — | — | US | disclosed |
| EP-1692108-A1 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058830-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058831-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058037-A1 | PICOLINYLPYRAZOLES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167631-A1 | Novel herbicides | DDT, CYP1A1, CYP1B1 | POLB 4171/4885KMT2A 1038/4885GAA 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.