Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 12/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 12/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | PRKCH | P24723 | 2/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442125 | 1.00 | PRKCQ (0.42) | PRKCQPRKCDSYKCDK2PRKCH | |
| SCHEMBL14538059 | 0.90 | PRKCQ (0.42) | PRKCQPRKCDSYKCDK2PRKCH | |
| SCHEMBL14538309 | 0.89 | PRKCQ (0.38) | PRKCQPRKCDSYKCDK2PRKCH | |
| SCHEMBL5446188 | 0.89 | IKBKB (0.44) | PRKCQPRKCDSRCIKBKBCHUK | |
| SCHEMBL5446183 | 0.89 | IKBKB (0.44) | PRKCQPRKCDSRCIKBKBCHUK | |
| SCHEMBL5445675 | 0.88 | NAMPT (0.41) | SYKCDK2SRCCCNE1FLT3 | |
| SCHEMBL5445672 | 0.88 | NAMPT (0.41) | SYKCDK2SRCCCNE1FLT3 | |
| SCHEMBL5445592 | 0.86 | CA12 (0.44) | PRKCQPRKCDSRCIKBKBCHUK | |
| SCHEMBL5445596 | 0.86 | CA12 (0.44) | PRKCQPRKCDSRCIKBKBCHUK | |
| SCHEMBL14490591 | 0.82 | PRKCQ (0.51) | PRKCQPRKCDCDK2PRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | ABL1, KDR, BCR | PRKCQ 434/4885PRKCD 459/4885SYK 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.