Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449952 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5446948 | 0.85 | MEN1 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5444720 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5442281 | 0.83 | CYP1A2 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5444157 | 0.83 | CYP1A2 (0.46) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL5444663 | 0.83 | CYP1A2 (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5452807 | 0.80 | CYP2C9 (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5451354 | 0.79 | CYP1A2 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5444382 | 0.78 | CYP1A2 (0.42) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL5444127 | 0.77 | MEN1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191395-A1 | Heterocyclic compounds having antifungal activity | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1717238-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191395-A1 | Heterocyclic compounds having antifungal activity | ERG28, MANBA, MAN2B1 | KDM4E 3019/4885ALDH1A1 1357/4885HPGD 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.