Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771104 | 0.91 | GRM5 (0.40) | EPHX1SMN1; SMN2LMNAGFERNPSR1 | |
| SCHEMBL14540542 | 0.91 | GRM5 (0.40) | EPHX1SMN1; SMN2LMNAGFERNPSR1 | |
| SCHEMBL4771120 | 0.91 | GRM5 (0.40) | EPHX1SMN1; SMN2LMNAGFERNPSR1 | |
| SCHEMBL4794135 | 0.90 | EPHX1 (0.46) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL14540867 | 0.90 | EPHX1 (0.46) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4793633 | 0.89 | EPHX1 (0.45) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4767981 | 0.88 | EPHX1 (0.43) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL5435036 | 0.88 | EPHX1 (0.47) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4769741 | 0.88 | EPHX1 (0.47) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL5441881 | 0.87 | EPHX1 (0.56) | EPHX1SMN1; SMN2LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2007-03-22 | — | — | US | claimed |
| WO-2007038138-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2007-03-22 | — | — | US | disclosed |
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2007-03-22 | — | — | US | disclosed |
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066584-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | EPHX1 378/4885SMN1; SMN2 3627/4885LMNA 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.