Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31088170 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL4215199 | 0.92 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HPGDMAPK1MAPT | |
| SCHEMBL4556782 | 0.89 | CYSLTR2 (0.51) | KDM4EMAOBMAPTCYP1A2CYP2C9 | |
| SCHEMBL31253976 | 0.86 | CTNNB1 (0.45) | KDM4EALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL6035440 | 0.85 | MAOB (0.68) | MAOBMAPTCYP2C19MAOACYP2C9 | |
| SCHEMBL1962771 | 0.85 | MAOB (0.64) | KDM4EMAOBMAPTCYP2C19RAB9A | |
| SCHEMBL1180883 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CYP3A4HPGDMAPK1MAOB | |
| SCHEMBL4145981 | 0.85 | TDP1 (0.49) | KDM4EALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL4207937 | 0.83 | PTGDR2 (0.51) | KDM4EALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL4215160 | 0.83 | MAOB (0.48) | ALDH1A1CYP3A4HPGDMAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021182896-A1 | INDUCED BROWN FAT DIFFERENTIATION COMPOSITION COMPRISING ISOLIQUIRITIGENIN DERIVATIVE | 가톨릭관동대학교산학협력단 | 2021-09-16 | — | — | WO | disclosed |
| US-20070037874-A1 | Manufacturing process of isoflavan or isoflavene derivatives | BICBIO CO., LTD. (KR) | 2007-02-15 | — | — | US | disclosed |
| WO-2005037815-A1 | A MANUFACTURING PROCESS OF ISOFLAVAN OR ISOFLAVENE DERIVATIVES | BICBIO CO., LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |
| US-5234951-A | Anti-ulcer agent comprising chalcone derivative | TSUMURA JUNTENDO, INC. (JP) | 1993-08-10 | — | — | US | disclosed |
| US-5106871-A | Reduced side effects | TSUMURA & CO. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0374789-A1 | 5- Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0292576-A1 | ANTI-ULCEROUS AGENT CONTAINING CHALCONE DERIVATIVE AS EFFECTIVE INGREDIENT AND NOVEL CHALCONE DERIVATIVES | TSUMURA & CO. (JP) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037874-A1 | Manufacturing process of isoflavan or isoflavene derivatives | CYP51A1, CYP2E1, CYP2F1 | KDM4E 2260/4885ALDH1A1 769/4885CYP3A4 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.