Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 15/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20485693 | 0.80 | FYN (0.65) | FYN | |
| SCHEMBL19467118 | 0.76 | IKBKB (0.44) | FYNIKBKBCYP3A4CYP2A6CYP2C9 | |
| SCHEMBL1055823 | 0.75 | FYN (0.67) | FYN | |
| SCHEMBL15254310 | 0.74 | DYRK1A (0.46) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL16554474 | 0.74 | DYRK1A (0.48) | FYNIKBKBCYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4695095 | 0.74 | FYN (0.67) | KDM4EFYNIKBKB | |
| SCHEMBL2950260 | 0.72 | FYN (0.59) | FYN | |
| SCHEMBL20485820 | 0.71 | FYN (0.62) | FYN | |
| SCHEMBL2947648 | 0.70 | FYN (0.61) | FYNLRRK2GRK5 | |
| SCHEMBL16554668 | 0.69 | FYN (0.43) | FYNIKBKBGRK5CAMK2DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049591-A1 | Inhibitors of MAPK/Erk Kinase | KALYPSYS, INC. | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049591-A1 | Inhibitors of MAPK/Erk Kinase | MAPK1, MAP3K1, MAP3K6 | KDM4E 3209/4885ALDH1A1 2598/4885LMNA 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.