SCHEMBL20485693

SCHEMBL20485693

CC(=O)c1cccc(-c2cnc3ccc(N(C)c4cccs4)nn23)c1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FYN P06241 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1055823 0.87 FYN (0.67) FYN
SCHEMBL18613580 0.81 FYN (0.61) FYN
SCHEMBL5445773 0.80 KDM4E (0.43) FYN
SCHEMBL2950855 0.79 FYN (0.68) FYN
SCHEMBL20485833 0.79 FYN (1.00) FYN
SCHEMBL22131017 0.78 FYN (1.00) FYN
SCHEMBL18613825 0.77 FYN (0.62) FYN
SCHEMBL20485820 0.77 FYN (0.62) FYN
SCHEMBL2950260 0.76 FYN (0.59) FYN
SCHEMBL14195064 0.76 FYN (0.77) FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180250297-A1 Methods, Compositions, and Uses of Novel FYN Kinase Inhibitors Pathways Neuro Pharma, Inc. 2018-09-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180250297-A1 Methods, Compositions, and Uses of Novel FYN Kinase Inhibitors FYN, LCK, PTK2B FYN 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.