Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5444912 | 0.98 | — | — | |
| Bromide SCHEMBL5439308 | 0.88 | MGAM (0.30) | — | |
| SCHEMBL5694057 | 0.87 | MGAM (0.31) | — | |
| Hydrochloric Acid SCHEMBL5439273 | 0.86 | MGAM (0.30) | — | |
| Hydrochloric Acid SCHEMBL28712022 | 0.76 | C5AR1 (0.40) | — | |
| SCHEMBL5691748 | 0.74 | MGAM (0.34) | — | |
| Hydrochloric Acid SCHEMBL5457189 | 0.74 | — | — | |
| Bromide SCHEMBL5455728 | 0.74 | — | — | |
| SCHEMBL1046763 | 0.73 | SLC22A12 (0.40) | — | |
| Bromide SCHEMBL5446117 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021615-A1 | Imidazolium salts that can be immobilized | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
| US-20070021615-A1 | Imidazolium salts that can be immobilized | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | disclosed |