Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694006 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL5445997 | 0.97 | — | — | |
| Bromide SCHEMBL5443576 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL5450117 | 0.85 | — | — | |
| Bromide SCHEMBL1882250 | 0.81 | SIGMAR1 (0.34) | — | |
| SCHEMBL17447703 | 0.81 | HRH3 (0.33) | — | |
| Bromide SCHEMBL1882150 | 0.80 | CRHR1 (0.32) | — | |
| Bromide SCHEMBL1658465 | 0.80 | MAPT (0.33) | — | |
| SCHEMBL16206227 | 0.80 | SIGMAR1 (0.35) | — | |
| SCHEMBL17447715 | 0.79 | HRH3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021615-A1 | Imidazolium salts that can be immobilized | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
| US-20070021615-A1 | Imidazolium salts that can be immobilized | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | disclosed |