SCHEMBL5445907

SCHEMBL5445907

S=C(Nc1ccc(Cl)cc1)Nc1ccc(Cl)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.75
KDM4E B2RXH2 2/20 0.75
NOX1 Q9Y5S8 1/20 0.69
ALDH1A1 P00352 5/20 0.67
GAA P10253 2/20 0.67
EPHX1 P07099 2/20 0.64
CNR1 P21554 1/20 0.64
THRB P10828 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MAOB P27338 1/20 0.59
NPSR1 Q6W5P4 4/20 0.58
LMNA P02545 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MEN1 O00255 1/20 0.57
HTT P42858 1/20 0.57
KMT2A Q03164 1/20 0.57
CYP3A4 P08684 1/20 0.56
TAS2R38 P59533 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956455 1.00 MAPT (0.75) MAPTKDM4ENOX1ALDH1A1GAA
Thiourea SCHEMBL1991944 0.93 MAPT (0.73) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL8956349 0.91 NOX1 (0.85) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL5081276 0.91 NOX1 (0.85) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL8956193 0.89 CNR1 (0.70) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL6811504 0.89 RAB9A (0.68) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL11074089 0.89 HTT (0.66) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL11060530 0.89 CNR1 (0.70) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL11277333 0.86 MAPT (0.64) MAPTKDM4ENOX1ALDH1A1GAA
SCHEMBL3860141 0.86 KDM4E (1.00) MAPTKDM4ENOX1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118685634-A Separation and recovery method for lithium ions in retired waste lithium batteries based on nanofiltration-reverse osmosis method 广东奥斯博膜材料技术有限公司 2024-09-24 CN claimed
CN-115532081-A Acid-resistant positive charge nanofiltration composite membrane and preparation method thereof 广东奥斯博膜材料技术有限公司 2022-12-30 CN claimed
US-4599630-A USING LEUCO DYES WHICH FORM TWO DIFFERENT COLORS WHEN HEATED AT DIFFERENT TEMPERATURES RICOH COMPANY, LTD. (JP) 1986-07-08 US claimed
CN-121609657-B Catalytic hydrogenation method of thiourea compound, ruthenium-based multi-tooth ligand compound and application thereof 浙江大学 2026-05-19 CN disclosed
CN-115532081-B Acid-resistant positive charge nanofiltration composite membrane and preparation method thereof 广东奥斯博膜材料技术有限公司 2025-10-28 CN disclosed
US-12427798-B2 Heat-sensitive recording composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
CN-119707777-A Synthesis method of asymmetric thiourea compound 浙江工业大学 2025-03-28 CN disclosed
US-20250001788-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
EP-4442468-A1 HEAT-SENSITIVE RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
EP-4442467-A1 THERMAL RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
US-20240326501-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US disclosed
US-4755831-A Multi-layer full-color thermosensitive sheet recording method RICOH COMPANY, LTD. (JP) 1988-07-05 US disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4620204-A MILTILAYER-SUPPORT, HIGH TEMPERATURE THERMOSENSITIVE LAYER, VINYLIDENE CHLORIDE INTERMEDIATE LAYER AND LOW TEMPERATURE COLOR FORMING LAYER RICOH COMPANY, LTD. (JP) 1986-10-28 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed
US-4599630-A USING LEUCO DYES WHICH FORM TWO DIFFERENT COLORS WHEN HEATED AT DIFFERENT TEMPERATURES RICOH COMPANY, LTD. (JP) 1986-07-08 US disclosed
US-4517580-A LEUCO DYES AND HALO-SUBSTITUTED DIPHENYLTHIOUREA COLOR DEVELOPERS;THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1985-05-14 US disclosed
US-4507670-A COLORING, IMAGES, LEUCO DYES RICOH COMPANY, LTD. (JP) 1985-03-26 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed