Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247817 | 0.86 | KMT2A (0.48) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL11739917 | 0.85 | ATM (0.61) | ATMKDM4ECA2POLBCYP3A4 | |
| SCHEMBL12715638 | 0.84 | ALDH1A1 (0.61) | ATMKDM4EPOLBCYP19A1CYP1A2 | |
| SCHEMBL10667947 | 0.84 | MAPT (0.48) | ATMKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL11801831 | 0.84 | TSHR (0.63) | CYP19A1CYP1A2CYP3A4KMT2AMEN1 | |
| SCHEMBL23112147 | 0.84 | MEN1 (0.47) | ATMKDM4EPOLBCYP19A1CYP1A2 | |
| SCHEMBL12978347 | 0.84 | MEN1 (0.47) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL14376706 | 0.82 | CYP3A4 (0.77) | KDM4ECYP1A2CYP3A4CYP2D6BLM | |
| SCHEMBL7323520 | 0.82 | PDE4B (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16641094 | 0.82 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101407474-B | Preparation of 2-bromo-4,5-dimethoxy benzenepropanenitrile | DONGHUA UNIVERSITY (CN) | 2011-12-14 | — | — | CN | claimed |
| CN-101407474-A | Preparation of 2-bromo-4,5-dimethoxy benzenepropanenitrile | UNIV DONGHUA (CN) | 2009-04-15 | — | — | CN | claimed |
| EP-0357565-A2 | New process for the synthesis of the levodopa | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-03-07 | — | — | EP | claimed |
| EP-3761950-B1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | IOULIA & IRENE TSETI PHARMACEUTICAL LABORATORIES IND AND COMMERCIAL S A (GR) | 2025-04-09 | — | — | EP | disclosed |
| CN-118112888-A | Colored photosensitive resin composition, color filter and display panel | 吉林奥来德光电材料股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) | 2023-04-27 | — | — | US | disclosed |
| EP-3761950-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | IOULIA AND IRENE TSETI Pharmaceutical Laboratories S.A. (GR) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019171088-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019171088-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2019-09-12 | — | — | WO | disclosed |
| US-10039764-B2 | Treatment and diagnosis of cancer and precancerous conditions using PDE10A inhibitors and methods to measure PDE10A expression | UNIVERSITY OF SOUTH ALABAMA (US) | 2018-08-07 | — | — | US | disclosed |
| US-20160143912-A1 | TREATMENT AND DIAGNOSIS OF CANCER AND PRECANCEROUS CONDITIONS USING PDE10A INHIBITORS AND METHODS TO MEASURE PDE10A EXPRESSION | UNIVERSITY OF SOUTH ALABAMA (US) | 2016-05-26 | — | — | US | disclosed |
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | MERCK PATENT GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | MERCK PATENT GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | MERCK PATENT GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
| EP-1720846-A1 | USE OF THIADIAZOLE UREA DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005085220-A1 | USE OF THIADIAZOLE UREA DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-09-15 | — | — | WO | disclosed |
| EP-0357565-A3 | NEW PROCESS FOR THE SYNTHESIS OF THE LEVODOPA | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-09-25 | — | — | EP | disclosed |
| EP-0357565-A2 | New process for the synthesis of the levodopa | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-03-07 | — | — | EP | disclosed |
| US-4900836-A | (3-amino-1H-pyrazol-4-yl) (aryl)methanones | AMERICAN CYANAMID COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| US-4129580-A | Resolution of certain asymmetric primary amines using lasalocid | HOFFMANN-LA ROCHE INC. (US) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039764-B2 | Treatment and diagnosis of cancer and precancerous conditions using PDE10A inhibitors and methods to measure PDE10A expression | PDE4A, PDE7B, PDE2A | ATM 1516/4885KDM4E 2333/4885CA2 1882/4885 |
| US-20230130823-A1 | PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF | BAD, BAX, PDCD4 | ATM 4020/4885KDM4E 3087/4885CA2 3093/4885 |
| US-20160143912-A1 | TREATMENT AND DIAGNOSIS OF CANCER AND PRECANCEROUS CONDITIONS USING PDE10A INHIBITORS AND METHODS TO MEASURE PDE10A EXPRESSION | PDE4A, PDE7B, PDE2A | ATM 1516/4885KDM4E 2333/4885CA2 1882/4885 |
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | RAF1, ARAF, JAK1 | ATM 91/4885KDM4E 4039/4885CA2 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.