Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | GUSB | P08236 | 1/20 | 0.60 |
| ▸ | CFTR | P13569 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454346 | 0.90 | L3MBTL1 (0.79) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5441846 | 0.89 | KMT2A (0.71) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5438412 | 0.88 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5446277 | 0.88 | KMT2A (0.83) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5456027 | 0.86 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5438337 | 0.86 | KMT2A (0.70) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5441810 | 0.86 | KMT2A (0.69) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5441695 | 0.84 | L3MBTL1 (0.78) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5475815 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5439861 | 0.83 | KMT2A (0.72) | KMT2AMEN1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | MERCK PATENT GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | RAF1, ARAF, JAK1 | KMT2A 1865/4885MEN1 1756/4885NPC1 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.