Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7368833 | 0.85 | — | — | |
| Diethylamine SCHEMBL2698 | 0.85 | — | — | |
| Diethylamine SCHEMBL3558785 | 0.85 | — | — | |
| Diethylamine SCHEMBL7130457 | 0.85 | TP53 (1.00) | — | |
| Diethylamine SCHEMBL9546417 | 0.82 | — | — | |
| Diethylamine SCHEMBL5689809 | 0.82 | — | — | |
| Diethylamine SCHEMBL9289074 | 0.80 | TP53 (0.89) | — | |
| Diethylamine SCHEMBL21585566 | 0.80 | — | — | |
| Diethylamine SCHEMBL5031686 | 0.80 | — | — | |
| Diethylamine SCHEMBL21585568 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268257-B1 | Process for producing tolterodine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-09-11 | — | — | US | disclosed |
| US-6180651-B1 | ANTIINFLAMMATORY AGENTS; ANALGESICS | BRISTOL-MYERS SQUIBB | 2001-01-30 | — | — | US | disclosed |
| WO-2000014082-A1 | DIARYLMETHYLIDENE FURAN DERIVATIVES AS DRUGS WITH ANTI-INFLAMMATORY, ANALGESIC AND CHEMOPREVENTIVE PROPERTIES | LABORATORIES UPSA (FR) | 2000-03-16 | — | — | WO | disclosed |
| US-5807873-A | Diarylmethylidenefuran derivatives and their uses in therapeutics | LABORATORIES UPSA (FR) | 1998-09-15 | — | — | US | disclosed |
| US-5688985-A | Process for producing keto nitrile derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0729941-A1 | Process for producing keto nitrile derivative and hexenone derivative | Takasago International Corporation (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5480987-A | 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5369102-A | B-lactamase inhibitors | AMERICAN CYANAMID COMPANY (US) | 1994-11-29 | — | — | US | disclosed |
| EP-0478874-A2 | Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1992-04-08 | — | — | EP | disclosed |
| US-5068232-A | Bactericides | AMERICAN CYANAMID COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| US-4105781-A | ANTIALLERGENS FOR TREATMENT OF ASTHMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |
| US-4049664-A | ANTIALLERGENS, ANTIASTHMATICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-09-20 | — | — | US | disclosed |
| US-4001280-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-01-04 | — | — | US | disclosed |
| US-3994918-A | ANTICONVULSANTS, TRANQUILIZERS | SANDOZ, INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3965122-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-22 | — | — | US | disclosed |