Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.74 |
| ▸ | PPARA | Q07869 | 15/20 | 0.74 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446280 | 1.00 | PPARG (0.74) | PPARGPPARARARBRARGRARA | |
| SCHEMBL4160131 | 0.95 | PPARG (0.81) | PPARGPPARARARBRARA | |
| SCHEMBL4155757 | 0.95 | PPARG (0.81) | PPARGPPARARARBRARA | |
| SCHEMBL4152666 | 0.94 | PPARG (0.72) | PPARGPPARARARBRARA | |
| SCHEMBL4152661 | 0.94 | PPARG (0.72) | PPARGPPARARARBRARA | |
| SCHEMBL4144220 | 0.92 | PPARG (0.69) | PPARGPPARARARBRARGRARA | |
| SCHEMBL5320006 | 0.90 | PPARG (0.92) | PPARGPPARARARBRARGRARA | |
| SCHEMBL5319716 | 0.89 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL5317275 | 0.89 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL4155845 | 0.88 | PPARG (0.71) | PPARGPPARARARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844015-A2 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079719-A2 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2006-08-03 | — | — | WO | disclosed |