SCHEMBL4152661

SCHEMBL4152661

CCOC(=O)c1ccc(C(=O)c2ccc3c(c2)C(C)(C)CCN3CCOc2ccc(CC(OCC)C(=O)OCC)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 17/20 0.72
PPARA Q07869 16/20 0.72
RARA P10276 3/20 0.51
RARB P10826 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4152666 1.00 PPARG (0.72) PPARGPPARARARARARB
SCHEMBL4155757 0.94 PPARG (0.81) PPARGPPARARARARARB
SCHEMBL5446282 0.94 PPARG (0.74) PPARGPPARARARARARB
SCHEMBL4160131 0.94 PPARG (0.81) PPARGPPARARARARARB
SCHEMBL5446280 0.94 PPARG (0.74) PPARGPPARARARARARB
SCHEMBL4144220 0.92 PPARG (0.69) PPARGPPARARARARARB
SCHEMBL4151653 0.90 PPARA (0.89) PPARGPPARARARARARB
SCHEMBL4151651 0.90 PPARA (0.89) PPARGPPARARARARARB
SCHEMBL5317275 0.87 PPARG (0.81) PPARGPPARA
SCHEMBL5319716 0.87 PPARG (0.81) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090124656-A1 Heterocyclic Oxime Compounds a Process for Their Preparation and Pharmaceutical Compositions Containing Them LES LABORATOIRES SERVIER (FR) 2009-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124656-A1 Heterocyclic Oxime Compounds a Process for Their Preparation and Pharmaceutical Compositions Containing Them GPR119, HBB, CYP3A7 PPARG 969/4885PPARA 1020/4885RARA 1550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.