Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447869 | 0.78 | PGR (1.00) | PGRAR | |
| SCHEMBL5435682 | 0.76 | PGR (1.00) | PGRAR | |
| SCHEMBL5439715 | 0.76 | PGR (1.00) | PGRAR | |
| SCHEMBL4423195 | 0.74 | PGR (0.60) | PGRAR | |
| SCHEMBL5123571 | 0.74 | PGR (0.59) | PGRAR | |
| SCHEMBL5123574 | 0.74 | PGR (0.59) | PGRAR | |
| SCHEMBL23783056 | 0.74 | PGR (0.57) | PGR | |
| SCHEMBL5441487 | 0.68 | PGR (0.53) | PGRAR | |
| SCHEMBL3985057 | 0.67 | PGR (1.00) | PGRAR | |
| SCHEMBL4612635 | 0.66 | AR (0.56) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066628-A1 | 5-Aryl-indan-1-ol and analogs useful as progesterone receptor modulators | WYETH (US) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066628-A1 | 5-Aryl-indan-1-ol and analogs useful as progesterone receptor modulators | PGR, CYP19A1, GNRHR | PGR 1/4885AR 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.