Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | VDR | P11473 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447205 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTVDRGFER | |
| SCHEMBL14490154 | 0.92 | SYK (0.49) | ALDH1A1HPGDMAPTVDRGFER | |
| SCHEMBL5438187 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTVDRGFER | |
| SCHEMBL5438195 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTVDRGFER | |
| SCHEMBL14490150 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTVDRGFER | |
| SCHEMBL5438765 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTVDRGFER | |
| SCHEMBL5438761 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTVDRGFER | |
| Hydrochloric Acid SCHEMBL5437586 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTVDRGFER | |
| Hydrochloric Acid SCHEMBL5437574 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTVDRGFER | |
| Trifluoroacetic Acid SCHEMBL5447005 | 0.87 | SYK (0.46) | ALDH1A1HPGDMAPTVDRGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | TARGEGEN, INC. (US) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149508-A1 | Six membered heteroaromatic inhibitors targeting resistant kinase mutations | ABL1, KDR, BCR | ALDH1A1 3322/4885HPGD 2433/4885MAPT 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.