Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447677 | 1.00 | LMNA (0.44) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL5448238 | 1.00 | LMNA (0.44) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL14501713 | 1.00 | LMNA (0.44) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL6410110 | 0.81 | LMNA (0.47) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL4592975 | 0.80 | LMNA (0.46) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL5441616 | 0.80 | LMNA (0.46) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL5443787 | 0.80 | LMNA (0.46) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL15012883 | 0.79 | LMNA (0.44) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL6236501 | 0.74 | LMNA (0.43) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL6233344 | 0.74 | LMNA (0.43) | LMNATSHRTP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507562-B2 | Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof | HYWE PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20070135526-A1 | Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof | LONG RANGE INTERNATIONAL USA LIMITED, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20060014987-A1 | Synthesis of beta-elemene, intermediates thereto, analogues and uses thereof | HUANG LAN | 2006-01-19 | — | — | US | disclosed |