SCHEMBL5448355

SCHEMBL5448355

CC(C)Nc1c(N)cnn1CC(O)CO

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAP2K1 Q02750 1/20 0.32
AHCY P23526 1/20 0.31
ADORA2A P29274 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5435421 0.90
SCHEMBL5431674 0.88 CSNK2A1 (0.30)
SCHEMBL5405131 0.87 PIK3CD (0.30)
SCHEMBL5441226 0.86 LMNA (0.34) ADORA2A
SCHEMBL5432824 0.86 TNK2 (0.30)
SCHEMBL14357635 0.84
SCHEMBL14357611 0.84
SCHEMBL5445681 0.83 MAPT (0.35) MAP2K1AHCYADORA2A
SCHEMBL5402403 0.82 MAP2K1 (0.32) MAP2K1AHCYADORA2A
SCHEMBL5441406 0.81 MAP2K1 (0.33) MAP2K1AHCYADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US claimed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed